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Polyvalent complexes for vaccine development
Homotypic interaction is a common phenomenon of many proteins, through which they form dimers. We developed a simple approach to turn small dimeric proteins into large polyvalent complexes for increased immunogenicity and functionality. This was achieved via a fusion of two or more dimeric proteins...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635153/ https://ncbi.nlm.nih.gov/pubmed/23498893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.02.041 |
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