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The G protein-coupled estrogen receptor (GPER) agonist G-1 expands the regulatory T cell population under T(H)17 polarizing conditions

The transcription factor Foxp3 is critical to the suppressive phenotype of CD4(+) regulatory T cells. Studies have clearly shown that numerous autoimmune diseases are marked by the presence of activated CD4(+) T cells within the setting of chronic inflammation. Therefore drugs capable of inducing Fo...

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Bibliografische gegevens
Hoofdauteurs: Brunsing, Ryan L., Owens, Kristin S., Prossnitz, Eric R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635139/
https://ncbi.nlm.nih.gov/pubmed/23502766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31828d8e3b
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