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The G protein-coupled estrogen receptor (GPER) agonist G-1 expands the regulatory T cell population under T(H)17 polarizing conditions
The transcription factor Foxp3 is critical to the suppressive phenotype of CD4(+) regulatory T cells. Studies have clearly shown that numerous autoimmune diseases are marked by the presence of activated CD4(+) T cells within the setting of chronic inflammation. Therefore drugs capable of inducing Fo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635139/ https://ncbi.nlm.nih.gov/pubmed/23502766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31828d8e3b |
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