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Cold pre-conditioning neuroprotection depends on TNF-α and is enhanced by blockade of interleukin-11

Cold pre-conditioning reduces subsequent brain injury in small animals but the underlying mechanisms remain undefined. As hypothermia triggers systemic macrophage tumor necrosis factor alpha (TNF-α) production and other neural pre-conditioning stimuli depend on this cytokine, we reasoned that microg...

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Bibliografische gegevens
Hoofdauteurs: Mitchell, Heidi M., White, David M., Domowicz, Miriam S., Kraig, Richard P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635118/
https://ncbi.nlm.nih.gov/pubmed/21070241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.07103.x
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