Effects of cyclophosphamide and IL-2 on regulatory CD4(+) T cell frequency and function in melanoma patients vaccinated with HLA-class I peptides: impact on the antigen-specific T cell response

The frequency and function of regulatory T cells (Tregs) were studied in stage II–III melanoma patients who were enrolled in a phase II randomized trial of vaccination with HLA-A*0201-modified tumor peptides versus observation. The vaccinated patients received low-dose cyclophosphamide (CTX) and low...

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Autors principals: Camisaschi, Chiara, Filipazzi, Paola, Tazzari, Marcella, Casati, Chiara, Beretta, Valeria, Pilla, Lorenzo, Patuzzo, Roberto, Maurichi, Andrea, Cova, Agata, Maio, Michele, Chiarion-Sileni, Vanna, Tragni, Gabrina, Santinami, Mario, Vergani, Barbara, Villa, Antonello, Berti, Emilio, Umansky, Ludmila, Beckhove, Philipp, Umansky, Viktor, Parmiani, Giorgio, Rivoltini, Licia, Castelli, Chiara
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634989/
https://ncbi.nlm.nih.gov/pubmed/23589107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-013-1397-7
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