Reactive Oxygen Species-Activated Nanoprodrug of Ibuprofen for Targeting Traumatic Brain Injury in Mice

Traumatic brain injury (TBI) is an enormous public health problem, with 1.7 million new cases of TBI recorded annually by the Centers for Disease Control. However, TBI has proven to be an extremely challenging condition to treat. Here, we apply a nanoprodrug strategy in a mouse model of TBI. The nov...

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Detalhes bibliográficos
Main Authors: Clond, Morgan A., Lee, Bong-Seop, Yu, Jeffrey J., Singer, Matthew B., Amano, Takayuki, Lamb, Alexander W., Drazin, Doniel, Kateb, Babak, Ley, Eric J., Yu, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634829/
https://ncbi.nlm.nih.gov/pubmed/23637912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061819
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