Microarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells

Cannabinoids are known to exert immunosuppressive activities. However, the mechanisms which contribute to these effects are unknown. Using lipopolysaccharide (LPS) to activate BV-2 microglial cells, we examined how Δ(9)-tetrahydrocannabinol (THC), the major psychoactive component of marijuana, and c...

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Detalhes bibliográficos
Main Authors: Juknat, Ana, Pietr, Maciej, Kozela, Ewa, Rimmerman, Neta, Levy, Rivka, Gao, Fuying, Coppola, Giovanni, Geschwind, Daniel, Vogel, Zvi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634783/
https://ncbi.nlm.nih.gov/pubmed/23637839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061462
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