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B-raf, a new member of the raf family, is activated by DNA rearrangement.

Complementary DNA clones of a putative transforming gene were isolated from NIH 3T3 cells transformed with human Ewing sarcoma DNA. The gene was termed B-raf because it is related to but distinct from c-raf and A-raf. It appears that substitution in the amino-terminal portion of the normal B-raf pro...

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Autors principals: Ikawa, S, Fukui, M, Ueyama, Y, Tamaoki, N, Yamamoto, T, Toyoshima, K
Format: Artigo
Idioma:Inglês
Publicat: 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC363468/
https://ncbi.nlm.nih.gov/pubmed/3043188
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