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Synthesis, Characterization, and in vitro Testing of a Bacteria-Targeted MR Contrast Agent

A bacteria-targeted MR contrast agent, Zn-1, consisting of two Zn-dipicolylamine (Zn-dpa) groups conjugated to a Gd(III) chelate has been synthesized and characterized. In vitro studies with S. aureus and E. coli show that Zn-1 exhibits a significant improvement in bacteria labeling efficiency vs. c...

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Detalhes bibliográficos
Main Authors: Matosziuk, Lauren M., Harney, Allison S., MacRenaris, Keith W., Meade, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634600/
https://ncbi.nlm.nih.gov/pubmed/23626484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejic.201101362
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