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In Vivo Light-Induced Activation of Neural Circuitry in Transgenic Mice Expressing Channelrhodopsin-2

Channelrhodopsin-2 (ChR2) is a light-gated, cation-selective ion channel isolated from the green algae Chlamydomonas reinhardtii. Here, we report the generation of transgenic mice that express a ChR2-YFP fusion protein in the CNS for in vivo activation and mapping of neural circuits. Using focal ill...

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Detalhes bibliográficos
Main Authors: Arenkiel, Benjamin R., Peca, Joao, Davison, Ian G., Feliciano, Catia, Deisseroth, Karl, Augustine, George J., Ehlers, Michael D., Feng, Guoping
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634585/
https://ncbi.nlm.nih.gov/pubmed/17442243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.03.005
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