Release of a phorbol ester-induced mitogenic block by mutation at Thr-654 of the epidermal growth factor receptor.

The tumor promoter phorbol ester (TPA) modulates the binding affinity and the mitogenic capacity of the epidermal growth factor (EGF) receptor. Moreover, TPA-induced kinase C phosphorylation occurs mainly on Thr-654 of the EGF receptor, suggesting that the phosphorylation state of this residue regul...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Livneh, E, Dull, T J, Berent, E, Prywes, R, Ullrich, A, Schlessinger, J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363427/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3136317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.6.2302-2308.1988
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