Prolyl 4 Hydroxylase: A Critical Target in the Pathophysiology of Diseases

Prolyl 4 hydroxylases (P4H) are iron- and 2-oxoglutamate-dependent dioxygenase enzymes and hypoxia-inducible transcription factor (HIF)-P4Hs play a critical role in the regulating oxygen homeostasis in the local tissues as well in the systemic circulation. Over a period of time, a number of prolyl h...

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Bibliografiske detaljer
Main Authors: Kant, Ravi, Bali, Anjana, Singh, Nirmal, Jaggi, Amteshwar Singh
Format: Artigo
Sprog:Inglês
Udgivet: The Korean Physiological Society and The Korean Society of Pharmacology 2013
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634087/
https://ncbi.nlm.nih.gov/pubmed/23626472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2013.17.2.111
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