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Divergent Roles of Amino Acid Residues Inside and Outside the BB Loop Affect Human Toll-Like Receptor (TLR)2/2, TLR2/1 and TLR2/6 Responsiveness

TLR2 specifically recognizes a wide range of ligands by homodimerizing or heterodimerizing with TLR1 or TLR6. However, the molecular basis of the specific signalling transduction induced by TLR2 homodimerization or heterodimerization with TLR1 or TLR6 is largely unknown. In this study, we found thre...

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Autors principals: Qiu, Yuan, Ding, Yan, Zou, Lingyun, Tan, Zhangping, Liu, Taiping, Fu, Xiaolan, Xu, Wenyue
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634009/
https://ncbi.nlm.nih.gov/pubmed/23626692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061508
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