Infrequent genomic rearrangement and normal expression of the putative RB1 gene in retinoblastoma tumors.

Retinoblastoma (RB) tumors develop when both alleles of a gene (RB1) are mutated and unable to function normally. Recently, Friend et al. [S. H. Friend, R. Bernards, S. Rogelj, R. A. Weinberg, J. M. Rapaport, D. M. Albert, and T. P. Dryja, Nature (London) 32:643-646, 1986] reported the cloning of a...

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Main Authors: Goddard, A D, Balakier, H, Canton, M, Dunn, J, Squire, J, Reyes, E, Becker, A, Phillips, R A, Gallie, B L
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1988
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC363388/
https://ncbi.nlm.nih.gov/pubmed/2898730
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