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Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevity

β-adrenoceptors are the common pharmacological targets for the treatment of cardiovascular diseases and asthma. Genetic modifications of β-adrenergic system in engineered mice affect their lifespans. Here we tested whether genes encoding for key components of the β-adrenergic signaling pathway are a...

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Detalhes bibliográficos
Main Authors: Zhao, Ling, Yang, Fan, Xu, Ke, Cao, Huiqing, Zheng, Gu-Yan, Zhang, Yan, Li, Jianxin, Cui, Hanbin, Chen, Xiaomin, Zhu, Zhiming, He, Hongbo, Mo, Xianming, Kennedy, Brian K, Suh, Yousin, Zeng, Yi, Tian, Xiao-Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633790/
https://ncbi.nlm.nih.gov/pubmed/23020224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12011
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