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Impaired neutrophil function in 24p3 null mice contributes to enhanced susceptibility to bacterial infections

Lipocalin 24p3 (24p3) is a neutrophil secondary granule protein. 24p3 is also a siderocalin, which binds several bacterial siderophores. It was therefore proposed that synthesis and secretion of 24p3 by stimulated macrophages or release of 24p3 upon neutrophil degranulation sequesters iron-laden sid...

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Main Authors: Liu, Zhuoming, Petersen, Robert, Devireddy, L.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633721/
https://ncbi.nlm.nih.gov/pubmed/23543755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202411
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