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2011 CCNP Heinz Lehmann Award paper: Cytochrome P450–mediated drug metabolism in the brain

Cytochrome P450 enzymes (CYPs) metabolize many drugs that act on the central nervous system (CNS), such as antidepressants and antipsychotics; drugs of abuse; endogenous neurochemicals, such as serotonin and dopamine; neurotoxins; and carcinogens. This takes place primarily in the liver, but metabol...

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Hlavní autoři: Miksys, Sharon, Tyndale, Rachel F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Canadian Medical Association 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633708/
https://ncbi.nlm.nih.gov/pubmed/23199531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.120133
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