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Evaluation of Digoxin Concentration after Loading Dose in Patients with Renal Dysfunction

BACKGROUND: Loading dose recommendations for digoxin are based on the volume of distribution, which is proportional to lean body weight, whereas maintenance dose recommendations depend on renal function. The volume of distribution of this drug is demonstrably reduced in severe renal dysfunction, but...

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Main Authors: Pawlosky, Nadia, MacDonald, Erika, Patel, Rakesh, Kanji, Salmaan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Canadian Society of Hospital Pharmacists 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633494/
https://ncbi.nlm.nih.gov/pubmed/23616674
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