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Evaluation of Digoxin Concentration after Loading Dose in Patients with Renal Dysfunction

BACKGROUND: Loading dose recommendations for digoxin are based on the volume of distribution, which is proportional to lean body weight, whereas maintenance dose recommendations depend on renal function. The volume of distribution of this drug is demonstrably reduced in severe renal dysfunction, but...

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Detalhes bibliográficos
Main Authors: Pawlosky, Nadia, MacDonald, Erika, Patel, Rakesh, Kanji, Salmaan
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Society of Hospital Pharmacists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633494/
https://ncbi.nlm.nih.gov/pubmed/23616674
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