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Molecular mechanisms underlying skeletal muscle weakness in human cancer: reduced myosin-actin cross-bridge formation and kinetics

Many patients with cancer experience physical disability following diagnosis, although little is known about the mechanisms underlying these functional deficits. To characterize skeletal muscle adaptations to cancer in humans, we evaluated skeletal muscle structure and contractile function at the mo...

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Detalhes bibliográficos
Main Authors: Toth, Michael J., Miller, Mark S., Callahan, Damien M., Sweeny, Andrew P., Nunez, Ivette, Grunberg, Steven M., Der-Torossian, Hirak, Couch, Marion E., Dittus, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633441/
https://ncbi.nlm.nih.gov/pubmed/23412895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01474.2012
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