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Novel pentablock copolymer (PLA-PCL-PEG-PCL-PLA) based nanoparticles for controlled drug delivery: Effect of copolymer compositions on the crystallinity of copolymers and in vitro drug release profile from nanoparticles

The purpose of this investigation was to design novel pentablock copolymers (polylatide-polycaprolactone-polyethylene glycol- polycaprolactone-polylatide) (PLA-PCL-PEG-PCL-PLA) to prepare nanoparticle formulations which provide continuous delivery of steroids over a longer duration with minimal burs...

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Detalhes bibliográficos
Main Authors: Tamboli, Viral, Mishra, Gyan P., Mitra, Ashim K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633208/
https://ncbi.nlm.nih.gov/pubmed/23626400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00396-012-2854-0
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