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Clinical Manifestations of α-Thalassemia
α-Thalassemia mutations affect up to 5% of the world’s population. The clinical spectrum ranges from an asymptomatic condition to a fatal in utero disease. Hemoglobin H disease results from mutations of three α-globin genes. Deletional forms result in a relatively mild anemia, whereas nondeletional...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633183/ https://ncbi.nlm.nih.gov/pubmed/23543077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a011742 |
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