L-type calcium channel targeting and local signalling in cardiac myocytes

In the heart, Ca(2+) influx via Ca(V)1.2 L-type calcium channels (LTCCs) is a multi-functional signal that triggers muscle contraction, controls action potential duration, and regulates gene expression. The use of LTCC Ca(2+) as a multi-dimensional signalling molecule in the heart is complicated by...

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Detalhes bibliográficos
Main Authors: Shaw, Robin M., Colecraft, Henry M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Spotlight Reviews: Spotlight on T-Tubules and Ryanodine Receptor Microdomain Signalling in Cardiac Hypertrophy and Failure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633156/
https://ncbi.nlm.nih.gov/pubmed/23417040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt021
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