EPR assessment of protein sites for incorporation of Gd(III) MRI contrast labels

We have engineered Apolipoprotein A-I (apoA-I), a major protein constituent of high-density lipoprotein (HDL), to contain DOTA-chelated Gd(III) as an MRI contrast agent for the purpose of imaging reconstituted HDL (rHDL) biodistribution, metabolism, and regulation in vivo. This protein contrast agen...

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Detalhes bibliográficos
Main Authors: Lagerstedt, Jens O., Petrlova, Jitka, Hilt, Silvia, Marek, Antonin, Chung, Youngran, Sriram, Renuka, Budamagunta, Madhu S., Desreux, Jean F., Thonon, David, Jue, Thomas, Smirnov, Alex I., Voss, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633150/
https://ncbi.nlm.nih.gov/pubmed/23606429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmmi.1518
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