Pharmacokinetic and pharmacodynamic characterization of a new formulation containing synergistic proportions of interferons alpha-2b and gamma (HeberPAG®) in patients with mycosis fungoides: an open-label trial

BACKGROUND: The synergistic combination of interferon (IFN) alpha-2b and IFN gamma results in more potent in vitro biological effects mediated by both IFNs. The aim of this investigation was to evaluate by first time the pharmacokinetics and pharmacodynamics of this combination in patients with myco...

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Main Authors: García-Vega, Yanelda, García-García, Idrian, Collazo-Caballero, Sonia E, Santely-Pravia, Egla E, Cruz-Ramírez, Alieski, Tuero-Iglesias, Ángela D, Alfonso-Alvarado, Cristian, Cabrera-Placeres, Mileidys, Castro-Basart, Nailet, Duncan-Roberts, Yaquelín, Carballo-Treto, Tania I, Soto-Matos, Josanne, Izquierdo-Toledo, Yoandy, Vázquez-Blomquist, Dania, García-Iglesias, Elizeth, Bello-Rivero, Iraldo
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633053/
https://ncbi.nlm.nih.gov/pubmed/23272809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-13-20
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