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Identification and analysis of conserved pockets on protein surfaces

BACKGROUND: The interaction between proteins and ligands occurs at pockets that are often lined by conserved amino acids. These pockets can represent the targets for low molecular weight drugs. In order to make the research for new medicines as productive as possible, it is necessary to exploit &quo...

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Détails bibliographiques
Auteurs principaux: Cammisa, Marco, Correra, Antonella, Andreotti, Giuseppina, Cubellis, Maria Vittoria
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633052/
https://ncbi.nlm.nih.gov/pubmed/23815589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S7-S9
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