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State of art fusion-finder algorithms are suitable to detect transcription-induced chimeras in normal tissues?
BACKGROUND: RNA-seq has the potential to discover genes created by chromosomal rearrangements. Fusion genes, also known as "chimeras", are formed by the breakage and re-joining of two different chromosomes. It is known that chimeras have been implicated in the development of cancer. Few pu...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633050/ https://ncbi.nlm.nih.gov/pubmed/23815381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S7-S2 |
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