Hypomethylation of host cell DNA synthesized after infection or transformation of cells by herpes simplex virus.

Infection of rat embryo cells with herpes simplex virus type 2 caused undermethylation of host cell DNA synthesized during infection. DNA made prior to infection was not demethylated, but some of its degradation products, including methyl dCMP, were incorporated into viral DNA. The use of mutant vir...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Macnab, J C, Adams, R L, Rinaldi, A, Orr, A, Clark, L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2837642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.4.1443-1448.1988
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