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Characterisation of the pharmacokinetics of ethinylestradiol and drospirenone in extended-cycle regimens: population pharmacokinetic analysis from a randomised Phase III study

OBJECTIVES: The primary objective of this analysis was to characterise the steady-state pharmacokinetics (PK) of ethinylestradiol (EE) and drospirenone (DRSP) in a randomised Phase III study that investigated the contraceptive efficacy and safety of three different regimens of EE 20 µg/DRSP 3 mg. ME...

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Detalhes bibliográficos
Main Authors: Reif, Stefanie, Snelder, Nelleke, Blode, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632974/
https://ncbi.nlm.nih.gov/pubmed/23493606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jfprhc-2012-100397
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