Enhancer and promoter elements directing activation and glucocorticoid repression of the alpha 1-fetoprotein gene in hepatocytes.

Mutations were introduced in 7 kilobases of 5'-flanking rat alpha 1-fetoprotein (AFP) genomic DNA, linked to the chloramphenicol acetyltransferase gene. AFP promoter activity and its repression by a glucocorticoid hormone were assessed by stable and transient expression assays. Stable transfect...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Guertin, M, LaRue, H, Bernier, D, Wrange, O, Chevrette, M, Gingras, M C, Bélanger, L
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363296/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2454390/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.4.1398
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