Effect of Farnesol on Growth, Ergosterol Biosynthesis, and Cell Permeability in Coccidioides posadasii

Coccidioidomycosis is a systemic mycosis caused by the dimorphic fungi Coccidioides spp. The treatment for chronic and/or disseminated coccidioidomycosis can be prolonged and complicated. Therefore, the search for new drugs is necessary. Farnesol is a precursor in the sterol biosynthesis pathway tha...

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Autores principales: Brilhante, Raimunda Sâmia Nogueira, de Lima, Rita Amanda Chaves, Caetano, Erica Pacheco, Leite, João Jaime Giffoni, Castelo-Branco, Débora de Souza Collares Maia, Ribeiro, Joyce Fonteles, Bandeira, Tereza de Jesus Pinheiro Gomes, Cordeiro, Rossana de Aguiar, Monteiro, André Jalles, Sidrim, José Júlio Costa, Rocha, Marcos Fábio Gadelha
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632934/
https://ncbi.nlm.nih.gov/pubmed/23459491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02457-12
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