Inoculum Effect on the Efficacies of Amoxicillin-Clavulanate, Piperacillin-Tazobactam, and Imipenem against Extended-Spectrum β-Lactamase (ESBL)-Producing and Non-ESBL-Producing Escherichia coli in an Experimental Murine Sepsis Model

Escherichia coli is commonly involved in infections with a heavy bacterial burden. Piperacillin-tazobactam and carbapenems are among the recommended empirical treatments for health care-associated complicated intra-abdominal infections. In contrast to amoxicillin-clavulanate, both have reduced in vi...

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Bibliographic Details
Main Authors: Docobo-Pérez, F., López-Cerero, L., López-Rojas, R., Egea, P., Domínguez-Herrera, J., Rodríguez-Baño, J., Pascual, A., Pachón, J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632932/
https://ncbi.nlm.nih.gov/pubmed/23439636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02190-12
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