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Comparative In Vitro Activities of GSK2251052, a Novel Boron-Containing Leucyl-tRNA Synthetase Inhibitor, against 916 Anaerobic Organisms
We studied the comparative in vitro activity of GSK2251052, a novel boron leucyl-tRNA synthetase inhibitor, against 916 clinical anaerobic isolates using CLSI methods. The GSK MIC(50)/MIC(90) for all isolates tested were 2 and 4 μg/ml, and the MIC(90)s against 302 Bacteroides fragilis and Bacteroide...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632912/ https://ncbi.nlm.nih.gov/pubmed/23459482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02580-12 |
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