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Comparative In Vitro Activities of GSK2251052, a Novel Boron-Containing Leucyl-tRNA Synthetase Inhibitor, against 916 Anaerobic Organisms

We studied the comparative in vitro activity of GSK2251052, a novel boron leucyl-tRNA synthetase inhibitor, against 916 clinical anaerobic isolates using CLSI methods. The GSK MIC(50)/MIC(90) for all isolates tested were 2 and 4 μg/ml, and the MIC(90)s against 302 Bacteroides fragilis and Bacteroide...

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Hlavní autoři: Goldstein, Ellie J. C., Citron, Diane M., Tyrrell, Kerin L., Merriam, C. Vreni
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632912/
https://ncbi.nlm.nih.gov/pubmed/23459482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02580-12
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