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Involvement of Fe Uptake Systems and AmpC β-Lactamase in Susceptibility to the Siderophore Monosulfactam BAL30072 in Pseudomonas aeruginosa

BAL30072 is a monosulfactam conjugated with an iron-chelating dihydroxypyridone moiety. It is active against Gram-negative bacteria, including multidrug-resistant Pseudomonas aeruginosa. We selected mutants with decreased susceptibilities to BAL30072 in P. aeruginosa PAO1 under a variety of conditio...

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Main Authors: van Delden, Christian, Page, Malcolm G. P., Köhler, Thilo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632904/
https://ncbi.nlm.nih.gov/pubmed/23422914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02474-12
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