Mutation and association analysis of GEN1 in breast cancer susceptibility

GEN1 was recently identified as a key Holliday junction resolvase involved in homologous recombination. Somatic truncating GEN1 mutations have been reported in two breast cancers. Together these data led to the proposition that GEN1 is a breast cancer predisposition gene. In this article we have for...

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Main Authors: Turnbull, Clare, Hines, Sarah, Renwick, Anthony, Hughes, Deborah, Pernet, David, Elliott, Anna, Seal, Sheila, Warren-Perry, Margaret, Evans, D. Gareth, Eccles, Diana, Stratton, Michael R., Rahman, Nazneen
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632835/
https://ncbi.nlm.nih.gov/pubmed/20512659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-0949-1
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