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Mutation and association analysis of GEN1 in breast cancer susceptibility
GEN1 was recently identified as a key Holliday junction resolvase involved in homologous recombination. Somatic truncating GEN1 mutations have been reported in two breast cancers. Together these data led to the proposition that GEN1 is a breast cancer predisposition gene. In this article we have for...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632835/ https://ncbi.nlm.nih.gov/pubmed/20512659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-0949-1 |
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