Molecular cloning and biological characterization of a human gene, ERCC2, that corrects the nucleotide excision repair defect in CHO UV5 cells.

The UV-sensitive Chinese hamster ovary (CHO) cell line UV5, which is defective in the incision step of nucleotide excision repair, was used to identify and clone a complementing human gene, ERCC2, and to study the repair process. Genomic DNA from a human-hamster hybrid cell line was sheared and cotr...

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Publicado en:	Mol Cell Biol
Autores principales:	Weber, C A, Salazar, E P, Stewart, S A, Thompson, L H
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1988
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363258/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2835663/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.3.1137-1146.1988
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