Regulation of Ribosome Biogenesis by Nucleostemin 3 Promotes Local and Systemic Growth in Drosophila

Nucleostemin 3 (NS3) is an evolutionarily conserved protein with profound roles in cell growth and viability. Here we analyze cell-autonomous and non-cell-autonomous growth control roles of NS3 in Drosophila and demonstrate its GTPase activity using genetic and biochemical assays. Two null alleles o...

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Bibliografiske detaljer
Main Authors: Hartl, Tom A., Ni, Julie, Cao, Jian, Suyama, Kaye L., Patchett, Stephanie, Bussiere, Cyril, Gui, Dan Yi, Tang, Sheng, Kaplan, Daniel D., Fish, Matthew, Johnson, Arlen W., Scott, Matthew P.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2013
Fag:
Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632458/
https://ncbi.nlm.nih.gov/pubmed/23436180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.149104
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