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Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models
Ribosomal stress is an important, yet poorly understood, mechanism that results in activation of the p53 tumour suppressor. We present a mutation in the ribosomal protein Rpl27a gene (sooty foot ataxia mice), isolated through a sensitized N-ethyl-N-nitrosourea (ENU) mutagenesis screen for p53 pathwa...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632393/ https://ncbi.nlm.nih.gov/pubmed/21674502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2891 |
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