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The adapter MAVS promotes NLRP3 mitochondrial localization and inflammasome activation
NLRP3 is a key component of the macromolecular signaling complex called the inflammasome that promotes caspase 1-dependent production of IL-1β. The adapter ASC is necessary for NLRP3-dependent inflammasome function, but it is not known if ASC is a sufficient partner, and whether inflammasome formati...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632354/ https://ncbi.nlm.nih.gov/pubmed/23582325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.02.054 |
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