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Increased apoptosis in osteoclasts and decreased RANKL immunoexpression in periodontium of cimetidine-treated rats

It has been demonstrated that histamine interferes with the recruitment, formation and activity of osteoclasts via H(1)- and H(2)-receptors. Cimetidine is a H(2)-receptor antagonist used for treatment of gastric ulcers that seems to prevent bone resorption. In this study, a possible cimetidine inter...

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Detalhes bibliográficos
Main Authors: Longhini, Renata, Oliveira, Priscila Aparecida, Souza Faloni, Ana Paula, Sasso-Cerri, Estela, Cerri, Paulo Sérgio
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632229/
https://ncbi.nlm.nih.gov/pubmed/23198931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joa.12011
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