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The human c-fps/fes gene product expressed ectopically in rat fibroblasts is nontransforming and has restrained protein-tyrosine kinase activity.

A 13-kilobase EcoRI genomic restriction fragment containing the human c-fps/fes proto-oncogene locus was expressed transiently in Cos-1 monkey cells and stably in Rat-2 fibroblasts. In both cases, human c-fps/fes directed synthesis of a 92-kilodalton protein-tyrosine kinase (p92c-fes) indistinguisha...

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Publicat a:Mol Cell Biol
Autors principals: Greer, P A, Meckling-Hansen, K, Pawson, T
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363183/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3352601/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.2.578-587.1988
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