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Pathway-based personalized analysis of cancer

We introduce Pathifier, an algorithm that infers pathway deregulation scores for each tumor sample on the basis of expression data. This score is determined, in a context-specific manner, for every particular dataset and type of cancer that is being investigated. The algorithm transforms gene-level...

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Autors principals: Drier, Yotam, Sheffer, Michal, Domany, Eytan
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631698/
https://ncbi.nlm.nih.gov/pubmed/23547110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219651110
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