Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

Large-scale proteomic approaches have identified numerous mitochondrial acetylated proteins; however in most cases, their regulation by acetyltransferases and deacetylases remains unclear. Sirtuin 3 (SIRT3) is an NAD(+)-dependent mitochondrial protein deacetylase that has been shown to regulate a li...

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Bibliografische gegevens
Hoofdauteurs: Rardin, Matthew J., Newman, John C., Held, Jason M., Cusack, Michael P., Sorensen, Dylan J., Li, Biao, Schilling, Birgit, Mooney, Sean D., Kahn, C. Ronald, Verdin, Eric, Gibson, Bradford W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631688/
https://ncbi.nlm.nih.gov/pubmed/23576753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302961110
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