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The Yeast Elongator Histone Acetylase Requires Sit4-dependent Dephosphorylation for Toxin-Target Capacity

Kluyveromyces lactis zymocin, a heterotrimeric toxin complex, imposes a G1 cell cycle block on Saccharomyces cerevisiae that requires the toxin-target (TOT) function of holo-Elongator, a six-subunit histone acetylase. Here, we demonstrate that Elongator is a phospho-complex. Phosphorylation of its l...

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Detalhes bibliográficos
Main Authors: Jablonowski, Daniel, Fichtner, Lars, Stark, Michael J.R., Schaffrath, Raffael
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC363168/
https://ncbi.nlm.nih.gov/pubmed/14718557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-10-0750
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