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PERSONALIZED PSA TESTING USING GENETIC VARIANTS MAY REDUCE UNNECESSARY PROSTATE BIOPSIES

PURPOSE: Recent studies have identified genetic variants associated with both increased serum PSA concentrations and prostate cancer risk, raising the possibility of diagnostic bias. By correcting for the effects of these variants on PSA levels, it may be possible to create a personalized PSA cutoff...

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Detalhes bibliográficos
Main Authors: Helfand, Brian T., Loeb, Stacy, Hu, Qiaoyan, Cooper, Phillip R., Roehl, Kimberly A., McGuire, Barry B., Baumann, Nikola A., Catalona, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631301/
https://ncbi.nlm.nih.gov/pubmed/23246478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2012.12.023
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