A Protein Prioritization Approach Tailored for the FA/BRCA Pathway

Fanconi anemia (FA) is a heterogeneous recessive disorder associated with a markedly elevated risk to develop cancer. To date sixteen FA genes have been identified, three of which predispose heterozygous mutation carriers to breast cancer. The FA proteins work together in a genome maintenance pathwa...

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Detalhes bibliográficos
Main Authors: Haitjema, Anneke, Brandt, Bernd W., Ameziane, Najim, May, Patrick, Heringa, Jaap, de Winter, Johan P., Joenje, Hans, Dorsman, Josephine C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631253/
https://ncbi.nlm.nih.gov/pubmed/23620800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062017
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