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Complexation of C6-Ceramide with Cholesteryl Phosphocholine – A Potent Solvent-Free Ceramide Delivery Formulation for Cells in Culture

Ceramides are potent bioactive molecules in cells. However, they are very hydrophobic molecules, and difficult to deliver efficiently to cells. We have made fluid bilayers from a short-chain D-erythro-ceramide (C6-Cer) and cholesteryl phosphocholine (CholPC), and have used this as a formulation to d...

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Main Authors: Sukumaran, Pramod, Lönnfors, Max, Långvik, Otto, Pulli, Ilari, Törnquist, Kid, Slotte, J. Peter
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631171/
https://ncbi.nlm.nih.gov/pubmed/23620740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061290
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