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Clinical evaluation of zaleplon in the treatment of insomnia

Zaleplon is a pyrazolopyrimidine hypnotic used for the treatment of insomnia. Zaleplon binds preferentially at the α1β2γ2 subunit of gamma aminobutyric acid type A (GABA(A)) receptors in the central nervous system, and has a half-life of about one hour. Efficacy studies show that zaleplon is a suita...

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Main Authors: Ebbens, Marieke M, Verster, Joris C
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630939/
https://ncbi.nlm.nih.gov/pubmed/23616704
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