Secretory Defect and Cytotoxicity: THE POTENTIAL DISEASE MECHANISMS FOR THE RETINITIS PIGMENTOSA (RP)-ASSOCIATED INTERPHOTORECEPTOR RETINOID-BINDING PROTEIN (IRBP)

Interphotoreceptor retinoid-binding protein (IRBP) secreted by photoreceptors plays a pivotal role in photoreceptor survival and function. Recently, a D1080N mutation in IRBP was found in patients with retinitis pigmentosa, a frequent cause of retinal degeneration. The molecular and cellular bases f...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Li, Songhua, Yang, Zhihui, Hu, Jane, Gordon, William C., Bazan, Nicolas G., Haas, Arthur L., Bok, Dean, Jin, Minghao
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Molecular Bases of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630842/
https://ncbi.nlm.nih.gov/pubmed/23486466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.418251
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki