Coactivation of Rac1 and Cdc42 at Lamellipodia and Membrane Ruffles Induced by Epidermal Growth Factor

A major function of Rho-family GTPases is to regulate the organization of the actin cytoskeleton; filopodia, lamellipodia, and stress fiber are regarded as typical phenotypes of the activated Cdc42, Rac, and Rho, respectively. Using probes based on fluorescent resonance energy transfer, we report on...

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Main Authors: Kurokawa, Kazuo, Itoh, Reina E., Yoshizaki, Hisayoshi, Nakamura, Yusuke Ohba Takeshi, Matsuda, Michiyuki
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2004
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC363057/
https://ncbi.nlm.nih.gov/pubmed/14699061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-08-0609
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