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Parkin promotes cell survival via linear ubiquitination

Mol Cell (2013) 49(5): 901–921 doi:; DOI: 10.1016/j.molcel.2013.01.036; published online 02 28 2013 Mitochondrial dysfunction has been linked to the pathogenesis of Parkinson’s disease (PD). PD-associated mutants of Parkin show defects in mitophagy, suggesting that Parkin exerts its neuroprotective...

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Bibliografske podrobnosti
Main Authors: Fiškin, Evgenij, Dikic, Ivan
Format: Artigo
Jezik:Inglês
Izdano: European Molecular Biology Organization 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630365/
https://ncbi.nlm.nih.gov/pubmed/23531882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.70
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