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IL-13-producing BLT1-positive CD8 cells are increased in asthma and are associated with airway obstruction

BACKGROUND: The role of CD8 T lymphocytes in the pathogenesis of asthma is not well understood. We investigated whether a subset of IL-13-producing BLT1-positive CD8 T lymphocytes is present in asthmatic airways and is associated with impaired lung function. METHODS: Bronchoalveolar lavage (BAL) cel...

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Detalhes bibliográficos
Main Authors: Dakhama, Azzeddine, Collins, Maureen L., Ohnishi, Hiroshi, Goleva, Elena, Leung, Donald Y. M., Alam, Rafeul, Sutherland, E. Rand, Martin, Richard J., Gelfand, Erwin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630251/
https://ncbi.nlm.nih.gov/pubmed/23573812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.12135
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